Actinic keratosis

Clinical features

• Erythematous, scaly papules; rough plaques
• Sun-exposed areas

Diagnosis

• Clinical appearance
• Biopsy if features of possible SCC (eg, size ≥1 cm, rapid growth, ulceration, tenderness)

Prognosis

• Chronic/persistent
• Progression to SCC
• Spontaneous resolution

Treatment

• Isolated lesions: cryotherapy
• Diffuse lesions: topical fluorouracil, imiquimod, tirbanibulin

SCC = squamous cell carcinoma.