HIV in infancy

Risk factors

  • High maternal viral load (eg, insufficient prenatal care, lack of antiretroviral therapy)
  • Breastfeeding by infected mother

Clinical
features

  • Failure to thrive
  • Chronic diarrhea
  • Lymphadenopathy, hepatosplenomegaly
  • Pneumocystis pneumonia
  • Prolonged/refractory candidiasis

Diagnosis

  • HIV DNA or RNA PCR

Treatment

  • Combination antiretroviral therapy