Secondary prevention of cardiovascular events in patients
with atherosclerotic cardiovascular disease

Lifestyle
modifications

• Complete smoking cessation*
• Dietary modification (eg, ↑ whole grains, vegetables, legumes)
• Regular exercise (>150 min/week)

Medical
therapy

• Blood pressure control <130/80 mm Hg**
• High-intensity statin therapy to achieve LDL <70 mg/dL
• Antiplatelet monotherapy
• GLP-1 agonist or SGLT-2 inhibitor for type 2 DM

*Greatest risk reduction for a single intervention.

**ACE inhibitor or angiotensin II receptor blocker preferred.

DM = diabetes mellitus; GLP = glucagon-like peptide; SGLT = sodium glucose transporter.