1. Explanation for HIV variant resistance to antiviral drugs?
a.CD4 is expressed on many cells.
b.HIV can bind many co receptors.
c. HIV reverse transcriptase is error free.
d.Nef is capable of dec cell surface expression of proteins.
e.rev efficiently exports viral mrna frm d nucleus.

2.A RCT compares d efficacy of methotrexate wid placebo fr initiating remission in crohns.
methotrexate placebo
no of patients 40 36
no in remission 26(65%) 14(39%)
Abs risk reduction 26.1%(95 % CI 4.4 to 47.8) p value 0.04. if stdy randomizes 1000 instead of 76. Expected impact on CI??
a.increas
b decrease
c. inc or dec

Is the ans fr 2 b coz increasin d sample size wud decrease d SEM. wat abt 1?

This is for the 2nd question.A larger sample size means a higher power of a Test/RCT.So a larger sample size makes us more confident about the results.Therefore the confidence interval tightens up.In other words confidence interval decreases.I think u have written CI referring to confidence interval.